"nor my Roland UA-101"
I use two UA-101 together (for recording, to get 16 tracks) without any problem.
But i use a dedicated laptop (HP DV7), and, when i upgrade, i make a complete reinstallation : first the OS (for me Win 7/64), then the MS updates of the OS, then the UA101 driver, then X1 and X1d, then X2, then X2a (so i have X1d and X2a side by side on my desk), then third-party plugs if needed.
No plugs from outside (except Voxengo Span and Flux Stereo Tools, and soon Fabfilter Deesser - and maybe Valhallaverb), which is easier since there is a lot of good included plugs (at least for me ! : Sonitus, PC2A, PC4K Comp and Gate, QuadCurve, Concrete Limiter, Breverb, etc), no internet, no wi fi, no bluetooth, nothing but OS and Sonar.
I didn't need to tweak the PC (although it is not actually up-to-date : i7 720 QM 1,6 MHz), and it is pretty stable.
I recommend everybody to be very
careful with tweaking and with modify the registry.
I bought my first PC in 1984 (a Compaq AT286 !), and i tweaked all my PCs a lot during all these years.
In fact, there were a real problem of performance in these days, but now, with the modern processors, the amount of ram, etc, i think that very often
"the cure is worse than the disease" (as we say in french).
Be careful also with third party plugs : it is sure that too many plugs, not enough checked, decrease the stability.
I remember 1984 : nobody could dream to have as much power in the box, and to run a software like X2 (even with its bugs !).
And when i worked in the studio in the early '70, it was absolutely unthinkable !
So i'am always amazed by it all.