Mr Yukon Gold,
Please detail the exact soft synths and presets you are talking about, and if you have perhaps a Sound Cloud or similar place to upload examples of the issue, it would make it much easier to understand what you are trying to explain.
It is just not enough information to go on at the moment.
Thanks - we are trying to figure out how to help you, and welcome to the forum by the way.
And Cakealex does not to the best of my knowledge work for Cakewalk - he is a long-time user. Some folks have different levels of tolerance for different thread etiquette matters, and it will always be that way. His point is valid, and has been made - a couple of times now.
So, I do not believe anybody in this forum can hazard a guess as to what is happening without more information as to exactly what you mean, and since the perception of sound is a bit on the subjective side - I repeat my suggestion that you find somewhere (YouTube, Sound Cloud, wherever) to post snippets of tracks exhibiting this "doesn't sound right" behavior.
Bob Bone