This is exactly the reason I wait to install the latest version of CAKE. I am not blaming the bakers because there are way too many permuations of hardware/software potential conflicts to test them all.
If it is their issue, they will fix it in time (most of the time). Then when the hotfix comes out, I upgrade. I don't have a lot of time to work on music and when I do, the last thing I want to be doing is chasing PC problems.
Sorry to hear you are having issues. One of things that I noticed with UAD x64 plugins, is a really strange delay, inserting plugs in real time while project is playing back. Use to work instantly, now the system goes dead for a few seconds (audio) and then pops back in. This has caused a crash a few times when the added plug didn't have enough UAD2 juice (all the DSP was used up). So, I need to lose the habit of inserting plugs while listening to tracks (even though this makes sense in my mixing metaphor).
One of the changes UAD made to in the x64 version, was to recompile the plugs to work with Apollo in super low latency mode. Each of the plugs had some global change made to them to have near zero latency in the APOLLO realm. Perhaps this is causing the new UAD behavior issues in Cake?
Jim