Reviving this old thread, I also have crackling when using TH2. Here's the situation: guitar track recorded with Garritan JABB. I have compared inserting Guitar Rig 4 and TH2. GR4 works smoothly without any audio glitches. TH2 generates crackles, pops, static, etc. If I freeze the track, the glitches go away. Because freezing the track eliminates the glitches, I'm guessing that TH2 is pushing my processor to its limits. This is very annoying, because I'm not running many tracks (about two dozen) with only a few plug-ins. I've got an AMD quad-core Phenom II x4 945 with 16 gigs RAM, which has been adequate for all other DAW purposes--as long as I don't run TH2. This leads me to the conclusion that TH2 is hogging memory or CPU cycles. I've got an M-Audio 2496 soundcard, current drivers, ASIO mode. I run Windows 7 64-bit and Sonar X2a. I've got Zone Alarm as my anti-virus/firewall, and I turn off the anti-virus module when I use Sonar. Is anyone else having good or bad experiences with TH2?