Bob - although MS say the error points to a bad disk image, it's also been known to crop up for other things. E.g. Adobe once put out a couple of bad/malformed/whatever dlls that were discovered to trigger it and fixed by an Adobe update.
It's the usual problem with Windows error codes - they rarely seem to point to just one thing. However, lots of people had problems with the Adobe dlls, and the forum doesn't seem to be over-run with X2a users having 0xc000007b errors.
Could be a third-party plugin dll though I suppose.
A hard disk check would still be my first port of call though, even if only for peace of mind.