dank
I have gone to Edit > Preferences >Audio>Driver Settings and scrolled to Mixing Latency. The buffer adjustments are grayed out.
If I understood your original post, the issue was with latency during recording.
To adjust your ASIO settings, you would set the sample rate and buffer size in the Presonus driver interface, try 44.1 and a buffer size of 64 or 128.
Then, go in to Sonar Preferences>Audio>Driver Settings, and make sure the sample rate matches what you set it to in the driver interface.
I have a Presonus interface, the Audiobox 1818 VSL, and I have no issues using 44.1 and a buffer size of 64.
Hope that helps - the other comments about plugins that have 'look ahead' processing, such as Perfect Space, etc, are also valid. You can test this by temporarily removing effects from your guitar track, and just play the raw signal while recording. If you hear no delay, then the issue would seem to be with one or more of the effects you have plugged in.
Bob Bone