One thing to consider is drive imaging software.
I use Macrium Reflect ( the free version ) and it's awesome.
This eliminates any problem with needing to re install Splat.
I could replace my hard drive, then restore my Macrium Image to the new hard drive and I'd be back up and running with everything exactly like it was when I made the image.
Have 1 dedicated OS installation (partition) for music work only.
Isolate your DAW partition from the internet in a way that you never get windows updates.
Been doing that for 3 yrs. or more with no problems at all with Windows 7 Pro 64bit
and quite a bit longer than that when I was only running Sonar 4 on XP 32bit.
Never had a problem because of not getting Windows updates.