MSE
Also run a detailed scan (with MSE) once a week. If anything is detected then I also run a scan with MalwareBytes which seems to almost always find something if MSE had already detected some issue.
I do this on both my primary DAW and a laptop. The DAW is connected to the net but not really for random browsing. Strictly DL, some forum (Cake, Ableton) stuff, and registrations...some Groove 3 videos but those are pretty rare. The laptop is used in a much looser fashion.
I also watch what is going on like a hawk. Any type of strange behavior and it is an immediate detailed scan as per above. As an example I was being redirected to an unexpected site when selecting a Google search result link. Immediate reboot and start scan process.
Regards,