I setup 3 screensets and tried it.
Unfortunately X2 will not *save* the window size and state (when the project is saved) for the PRV in 2 specific areas, and this is even after locking the specific screenset and then saving the project.
The areas it won't remember are: 1) The width of the side panels, and more importantly, the left controller list / piano keyboard panel.
2) Most importantly it won't save/remember the height of the controller pane after it's been dragged up most of the way.
3) I'm also seeing many crashes when switching screensets before they are locked and the project is saved / reopened.
So although screensets is a step in the right direction for this workflow, I think we're dealing with an incomplete beta version here in X2.
Hopefully they'll get it working properly. I'll be waiting a while to see. Evaluation is finished with no sale.
Also, luckily I'm still way ahead of X2 with the functionality of 4.0.2.
4.0.2 literally smokes X2 for large scale midi production in my opinion (128+ tracks - 10 or more PRV pinned open)
It looks more defined, has many hot keys*** that have been removed from X2
and it's only down side that I see is it can't run on Win7 Pro. ( or can it ??? where's the fix for that? )
*** CTRL+TAB to flip through open windows
ALT+W+number to switch between open windows.