OK, the weird thing is solved.
That humming came from having cables plugged into the audio interface with a DI box at the other end, which was switched off since it was not in use. With the DI on, the USB noisy interference when moving windows is gone ... strange, and beyond my current understanding of the world, but true ...
What still puzzles me is if this would also be the case if the USB cables are pluuged into a separate USB PCI interface and not the motherboard??? Any suggestions???
As regards the original NVIDIA problem: Despite trying all of most welcome suggestions, it's still the same. So I ordered an 5450 card which I will give a try in a few days.