I run an Audio Box 1818 VSL with no problems.
My interface settings are:
1 Run at Startup is checked
2. ASIO Sample Rate is 44.1 khz
3. ASIO Buffer size is 256
In X2, I specify ASIO mode, and use the Audiobox 1818VSL ins and outs.
PTheory, I will momentarily send you a private message with my email and cell, so that you can call me at your convenience today. I know it's turkey day here, but I have no problem walking you through things so please feel free to call.
Bob Bone