Keep in mind I'm using a i7 Quadcore and 64 bit Windows 7 X2 Producer 64 bit..... This link here really helped:
http://www.cakewalk.com/Documentation/default.aspx?Doc=SONAR%20X2&Lang=EN&Req=INI_Files.6.html ,,,, The three changes that seemed to be important were changing the plugin buffs setting to (128 ) and thread scheduling model to ( 2 ) this is for folks with quad processor and drop out ms to 500. now go through and read the description on all of them ,,,, Those three seemed to be important to my system,,,,,, Before I found this info ,, I was only having problems as the project got bigger and bigger( more plugins more tracks more overall CPU load). then More problems would start popping up ..... since these changes I worked all day yesterday with not one crash and I could even open V-Vocal with success on that same big project ..... Try it and see if it works for you .