Walt,
With the amount of plug ins on each track you have, are you using "Plug in load balancing" ?
Try doing a test by disabling it/or enable it and try your tests again.
With 5 plug ins per track, this sounds like a great candidate for load balancing.
In my projects I use a good amount of tracks (between 35-50) and quite a bit of plug ins and I don't see a big difference in time duration when closing large projects and smaller ones. a few seconds at best.
Im, not seeing any RAM being unloaded. I have however, seen devices that hold my system hostage until they feel like letting go. This can be an audio device or a midi controller.
You can try removing all your devices and doing the same tests.
Also a bit of advise, if you are using 5 plug ins per track on multiple tracks, you may want to consider busing/routing options.