Pwal, I just tested a VST 2.4 compatible plugin called "The Glue" with its sidechain feature, in X2, and it worked perfectly.
I added this compressor at the end of a lead vocal bus and enabled its sidechain feature. I then added a send on a kick drum track and indeed the sidechain input of The Glue (on the vocal bus) showed up in the list to choose from/send to. Worked great.
The Glue is one of the best bus compressors (SSL circuit modeled) around, too. Its sidechain also has a nice HP filter that you can use to control its detector. It can also be used for general purpose compression duties, of course. But, it's also a mastering-grade tool suitable for the 2bus.
Morgan Page (a chart-topping EDM producer) uses The Glue for just this application (in Protools, which also does not have VST3). He shows it in action and speaks highly of it in this video (about 2:15 minutes in):
http://www.youtube.com/watch?v=_gzKWRzCM4k Here's The Glue by Cytomic:
http://cytomic.com/glue I'm sure other VST2.x compressors with sidechain abilities would also work.
Update/edit: Waves C6 Sidechain, sadly, does not work in non-VST3 hosts (the sidechain feature, that is). It could, but doesn't. Waves has chosen to abandon VST2.x for all its sidechain features. I also confirmed this with the Waves API2500. Its sidechain does not work in non-VST3 hosts (like X2). I then tried the API2500 in Studio One v2 and it works as expected. It shows up neatly in a section called "sidechains" at the end of the bus drop-down (nice!). I also tested the VST2.x The Glue in Studio One and it also works, and also shows up in this "sidechains" section. Man, Studio One v2 is looking NICE, I gotta say.
Back to X2. I also saw the sidechain inputs of all Softube compressor-based products show up in X2 (FET, Summit Audio, Tube-Tech, etc.). So, there are plenty of good 3rd-party sidechain options compatible with X2 (just not Waves products, which sucks).