Hi Marcus,
I do have the full GR 5 and the TH2 that comes with the X2 pro (shame on me I have not even open TH2 yet..!)
But my strat become too noisy with the GR 5 patches, so I just do a simpler setup as in my (top) post above. I think it has got to do some line noise in my place and I have to turn down the treble to min, combined with the gate effect, so the overdrive sound won't be that noisy (hiss and static sound).
Regarding the DR880 drum machine / guitar effects, I was just playing around the idea of recording clean while monitoring with out board effects, but is not necessary now as I'm ok with the setup above.
Thanks for the link above, I can simply swap in the effects in place of the Studio Devil BVC.