Piangio,
I had trouble with drop outs after upgrading to X2 for a bit. I found that I had to change my settings in Preferences > File > Audio Data > Render Bit Depth 24
I often use 24 bit 88.2 when recording. I find that when I use this resolution and an amp sim that sometimes I get drop-outs. You can freeze the track to reduce these issues too.
I don't mean to suggest that this is your problem, but I'm telling you it was mine and the solution was to reduce the render bit-depth.
You can see the bit depth of a clip by right clicking it and choosing the bottom selection of associated audio files. This will show the bit depth but not the sampling rate. You can play with your sampling rate too if you get lots of freezing.
I like to use 88.2 but when I really can't afford a drop out, I consider tracking at 44.1 if it is sufficient (usually is fine for the work I do).