I'm glad someone asked this question as I been thinking the same thing. In the past with Xp I was a huge fan of when things get sluggish and weird, pull the Hard drive, put a fresh ( usually bigger) drive in and fresh install. There was always a huge improvement in performance.
I did the in place upgrades on my office and my DAW machines,They are ..OK.. but in November I was given an i7 HP desktop and to tune it up I put in an SSD drive and a fresh install of W10. It is noticeably way faster and very responsive. All 3 computers have the same SSD drives and 16 GB of RAM, the only difference would be the processors. An i3 and i5 and the i7. The i5 is my DAW and has become the one I find always hanging up and takes the longest to boot. I'm not talking about using Sonar, I'm just talking about slow to boot, slow to settle down slow to open web pages etc.
So I'm in the mood for a fresh install on my DAW just to perk it up.
While I'm at it I can upgrade the OS SSD which is 3 years old now and another habit of mine was keeping OS dives fresh.