If I'm doing 4/4 stuff, and I like my measure numbers to "add up" or work in groups of four measures/bars, I create four measures that are just a quarter note long, that is 1/4 time sig.
That way, I'm not waiting forever for my song to start but my song starts at measure five and from then on my measure numbers stack up.
Also, for me, I used that delay to the start of the song to send all the necessary MIDI messages to all my MIDI hardware.