Keith Albright [Cakewalk]
SSDs work until they don't. Because of limited (which improves with each gen) write cycles you want to avoid filling them. Why? Because they do wear leveling. So imagine if you run them close to full, they will be thrashing fewer cells more often and wearing them out sooner. The higher capacity ones can store multiple values in a cell which means less potential for measuring the different values over time as the full capacitive charge degrades. So, do your homework to be sure you get ones that are better quality and for critical work you may want to get single level cell rather than multiple. No question the speed improvements are huge and worth it. Just be aware of how you use them. Generally not a good idea to run a defragment on them.
Whilst this is somewhat true, the Samsung Pro Evo range guarantees the drive against failure and slowing down through use for some insane amount of writing/gigabytes. My point being...some drives are more equal than others.
To answer the OP question...I use an SSD drive as my boot drive, and I also have a portable USB drive connected to a USB 3 port as my audio/video drive. All my virtual instrument samples are on my boot drive (Notion by Presonus, Grand Rhapsody by Waves 14gig :), Dim Pro and a couple of others) - it isn't huge only 256 gigs, but it seems to be enough. I still have over 80 gigs free. I'm lucky because my ACER Nitro laptop also has an internal spindle drive for storage.
To gauge how useful an SSD drive is for audio. My last composition
https://soundcloud.com/aaudiomystiks/sonata-no7-organik-mirrorball-blues had 60 tracks of 64bitfp 48khz audio, and I was only just starting to max out my system...it probably had some headroom, but I think I'd reached the threshold of throughput, probably not ram (32 gig) or CPU. I suspect if I had a thunderbolt portable drive or an internal SSD drive my track count could have been higher. When I was trying to mix a track a few weeks ago on my old laptop...I could barely get past 20 tracks of 64bitfp 44.1khz audio, let alone 60. I certainly could not mix and master at within the same project, like I did on the above link, which is what I like to do.
Hopefuly that answers the OP question.
Ben