Thanks, Clark, for answer. In fact it is not new issue for me. I observed it earlier but it was not 'critic' so I used some workarounds (like adding additional bar to project).
But curiosity made me to test all possibilities (in fact not so many only 4). I am turning on/off only 2 buttons (Metronome During Playback and Metronome During Recording) and only 1 of 4 has such mysterious issue.
I tested toggling FX as you suggested, no difference. Interesting as I reinstalled OS from scratch so I would rather expect solving strange issues. I will try to check this on the same machine with different OS and using different audio interface I have secondary profile for machine for less serious applications.