Wonderfully glorious mistakes and accidents.....
I made some interesting progress as a beginning guitarist when I was playing around with a knife or some other sharp tool and cut my fingers on my fretting hand. Nothing that required stitches, but painful enough that I couldn't fret the strings with certain fingers. In order to keep playing, I had to make some accommodations to how I fretted the chords.... Something that I would probably not have done otherwise. I still use what I learned back then in my playing now.