+1 - Switch to Chrome... It puts Firefox to shame.
You should have next to 0 latency with the RME (at least according to RME) so you must have it configured incorrectly.
Are you using ASIO mode set for 128 or 256 samples?
Are you monitoring through the RME?
Are you recording at 24 bit depth and 44.1KHz sample rate?
Do you have Use MultiProcessing engine selected? Try it both ways.
Do you have Use MMCSS selected? You should for Win 7
Give us some info about your configuration.