You can trigger SI Drums and EZ Drummer from your controller.
While I have used the loops, my preferred method is to trigger the individual drums via a controller( either my PCR-M50 or DM6 drum kit)
You will need to have Input Echo enabled to hear the drums (or any synth) as you play live.
Do you have a proper interface?
If you are using the stock sound card, you will most likely experience a very annoying delay(latency).
For low latency performance when playing synths(including drum samplers), a decent interface is essential.
On a side note, .tif files are visual, often animated, and have nothing to do with sound.
I suspect you will have more questions. Please ask, and we will help as much as we can.