I use a lot of x32 plugs, along with x64 plugs, I use jBridge and Automap, and multiple hosts, each having their own set of plugins properly organised in folders and subfolders, no matter how messed up my plugin installations went over the years....
I wrote a utility which organises and manages everything for me. Bit geeky, but maybe you want to try?
http://www.familiekraft.de/PluginManager