Best: Okay, considering the forum (but absolutely no lie) Sonar 6 PE. Wow, this is cool. I've got Pyro 2003 I think it is and mine works great. Cleaned up a ton of vinyl with it.
Started with Mesa Boogie in the early 80's and still own a Mark IV and a Studio Caliber. Cool! My early 80's Schecter Bass and guitar necks on Frankenstein guitars. Still wonderful. EMG active pickups! 72 Martin 0-16 N. Y. (the one Ian Anderson uses) wide straight neck and records like butter. Cream machine and Rockman X-100, still very useful. Roland VG-8EX, a little digital sounding but wow, I can do tunings and 12 string without messing with that, great! Roland guitar synth, the one from several years back, tracks pretty good and has some of the sounds from that GR-700/G-707 setup I used in the 80s.
My 60's Ludwig drum kit, fun to beat on although I don't have the chops to record, I can now sample it and stick it into songs thanks to Session Drummer-2. Alesis QSR 8.1, piano feel and pretty easy to figure out. Roland D-10, still the best synth action keybed I've played.
Avalon 737 (Mercenary edition), RNC/RNP, Grace 101, Alesis Midiverb II, etc; gots to has some outboard. AKG 414 B/ULS, Rode tube mic, all the Shure SMs, AT 3035 etc, have been cool.
I really really dig my EMU 1212 sound card and the Emulator X software. Very cool and with synth swipe I am putting hardware sound mods on ebay. Stedman pop filter- sometimes the little things make a big difference. F. Alton Everest, man his book got my recording room sounding very much better. Yammy NS-10M Studio's and Auratones, since I started using them and learning them in the early 90's my mixes have translated much better. Mackie mixers; the older 'made in USA' ones are rock solid. Selmer Mk VI sax is needing some minor repairs, but still amazing coming from around 69 or 70.
For live, Crown power amps, JBL, McCauley and Renkus Heinz drivers rock! Never let me down.
Bad purchases: I bought an Orange amp in the late 70's. Coolest looking thing in the world but you could just tell it was fixing to blow and it did right after I traded it in on a Marshall. Earth mixing board and Alesis monolithic mix board. Both total pieces of crap. Monster cable; overpriced, made no difference garbage. Egg cartons on walls, man I can't believe I did that. Fabric pop filters, what a waste (see Stedman post above). Late 70's and on Gibsons, they moved the factory to Nashburg from Kalimazoo and the guitars just went to hell. I had a bud who worked there for a spell and I reckon I know why. Most of the Chinese mics. Just listen!!!