I think a few of these have been mentioned already, but MY wishes include:
(01) "Friendlier" friendly names for drivers. There's a whole other thread in the forum about how "another" DAW is doing it better, and I really like that implementation: let us configure the name completely for both mono/stereo pairs (maybe also surround groupings?) and also let us configure how they appear on the input/output menus. That would save a LOT of clicking and confusion in making those selections, particularly when adding new buses to the project.
(02) Work on the Control Bar customization so you don't need a monolithic display screen to see EVERYTHING at once. I like the idea of size customization. I also like the idea of custom CB modules. Scrolling would be fine, though I think I'd prefer a pagination if that was really the solution they wanted. I agree with whoever said 8.5 had this concept figured out: those tool bars were customizable and I had access to all functions with a similar amount of screen space that I use now for less than half.
(03) Speaking of toolbars, I'd like basic program-level functions on the CB again: "New", "Open", "Save", "Close" would be good for me. "Save As" would be nice as well.
(04) Automation modes. I'm not optimistic about this, having been hoping for this since version 7. Right now we have "Read" and the equivalent of "Touch Write" (and "off", I guess). I'd really love it if there was also a "Latch Write" and "Overwrite" (i.e., "erase last envelope and start a new one") modes. A "Trim" automation mode would also be handy. Since I've acquired a Mackie MCU, these functions would really open up the abilities of that unit to improve my workflow.
(05) Speaking of the MCU, I'd also really love it if the Pro Channel modules were ALL accessible using the MCU and/or C4, and NOT just the first PC module in the chain. There's no more "standalone" EQ OTHER than Pro Channel, and if you don't have Expanded you can't adjust the order of PC modules: you could use the EQ mode in the MCU/C4 to control Pro Channel functions and scroll through them as well.
(06) Speaking of Pro Channel, I'd also like it if the Pro Channel modules could be put in a floating window: right now I can't see them all in Inspector, and it's kind of awkward to find them on the Console View.
(07) Speaking of the Inspector, it would be great if that was scrollable. That way it's less an issue to find a particular parameter of the given channel in Track View.
That looks like a lot but it's mostly usability tweaks. I like to think those particular features wouldn't be as difficult to implement as some of the other common requests (I'm no expert though): if Cake were to add ONLY that to X2 over X1, I think it'd probably be worth the usual $100 upgrade for me.