What driver mode are you using? Duo Capture has proper ASIO drivers written for it, I think, so that's what you shuld use. What's your latency set at?
Have you played with different buffer sizes?
The 32 bit SONAR can only use about 3 gigas of RAM, so the extra 5 gigas doesn't help in this case.
As you have used that set up successfully this far, before the hardware upgrade, I assume you have no resource eating apps running in the background.
OTOH, ASIO can only use only one interface at a time, so I wonder if Duo Capture and UM-2G cause a conflict operating simultaneously? If so, using WDM driver should/could help.