Man, feel like I dodged a bullet. I upgraded to Windows 10 today and lost interaction through my firewire port to my Saffire Pro 40. The 1394 just acted like there was nothing there - no connect/disconnect indication, etc., even though the Saffire showed an active firewire connection (probably just a hardware thing, like an ethernet light). In addition, my on-board audio (that runs my little PC surround sound speaker system) was not able to produce 5.1 surround - rear speakers would not work but front, center, and sub were good.
I played for hours with complete driver and app uninstalls, power-down, re-installs (for both the on-board audio as well as the firewire)... no joy. I even tried the Windows 8/8.1 legacy 1394 OHCI for shizzengiggles - newp. Even though Focusrite's website says the Saffire line is ready for Windows 10, my experience says otherwise.
The good news is, the roll back is super-quick - took about ten minutes - and everything is working well again.
It's a damned shame too, cuz I was liking a lot of what I was seeing in the interface (although some things are maddening - I felt like they were actually trying to hide the device manager "button" ... and I needed it a LOT).
Needless to say, I could/did not test how all my plugs would behave - I was too busy yelling in Python voice "RUN AWAY! RUN AWAY!"
So it's Win 7 for me for a while until real support materializes. Makes me laugh at the reports that MS is getting serious about audio... how about a little help on the firewire guys, and don't play the it's old tech card here... there's lots of installed base out there. A serious race car has a rear view mirror.
Steve