I think I posted about this a while ago but it's also a good idea to turn your monitor up to maximum brightness and dim it via f.lux. The reason is because modern LCD monitors achieve lower brightness levels by turning the pixels on and off to a pulse. The lower the brightness, the lower the pulse width. So if you set your monitor brightness control to anything less than 100%, the screen flickers. This flickering can cause eye problems and headaches.
Adjusting your screen's brightness at the software level is totally different, there is no pulsing. This was a revelation to me because the first thing I've always done when I get a new monitor is turn the brightness down with the monitor controls - 100% is usually way too bright. I had no idea this might have been contributing to my eye fatigue and headaches, you'd think the opposite would be true.
f.lux can reduce your monitor brightness via two hotkeys, Alt-PgUp/PgDn. This is different from the color warming that is f.lux's main function - it doesn't yellow the screen, it just lowers the brightness. So I have f.lux both warming the colors at night AND lowering the brightness at all times. I feel so much better for it.