I bought Focusrite Scarlett 2i2 (2nd gen) specifically because I only ever record my guitars DI (apartment life), and out of the sound cards in the price range of 300 dollars, that one has the lowest latency. Focusrite Scarlett 2i2 (2nd gen) has 2ms roundtrip latency, whereas my Roland Quad Capture has 18ms, and cost twice as much. Half the price for a 10th of the latency, hopefully. Still waiting for them to send it.
On topic: I completely disabled my internet, restarted my computer, opened up a project in Sonar Platinum, set it to loop, drove to Tim Hortons, ran through the grocery store, came back 25 minutes later and my audio had dropped out.
With my computer specs, playing projects only ever takes up 20% of my CPU usage, at most, so I don't understand how it could be a CPU interruption or something of that nature. I'm not lacking processing power. So, in my mind, it must be a driver.