Pianos will nearly always have resonances to deal with. Use the trusty band-sweep method to identify them. Create a bandpass filter, set it to a narrow Q and boost it way, way up. The piano will now sound awful. Sweep the filter back and forth until you find the spot where it sounds the absolute worst, which is often between 800 and 1500 Hz, or around 4 KHz. Then widen the band a little and change its gain to a negative value, -3 to -6 dB is usually enough but it might take more - just don't make it so negative that it starts sounding thin. Even the annoying frequencies have to be in there for a full sound.
Piano trick #2 is the air band, up above 8-10 KHz. A little boost up there can help definition, but it depends on the samples. On some libraries, it just gets plinky. And if the samples don't have a lot of high frequency content to begin with, this won't help anything.
Piano trick #3: HPF. This will depend on where your piano sits in the mix. If it's the main featured instrument, don't bother. But if it's more of a rhythm instrument competing against guitars, roll off that bottom below ~100 Hz. I often have piano intros in my songs, so I automate the HPF to give the piano full range for the intro and then slip down into the mix.
Piano trick #4: compression. I know, that's sacrilege if you're a piano player, but it can help with sustain. You can also use the sidechain filter (if your compressor has one) to soften the hammer noise.