Hi,
First of all, don't think you are the only one who gets depressed about music. I have gotten so sick of LA BS at times I shoved the whole lot in the corner and considered selling all of it.
Then I hear something that catches my ear and I have to drag out the guitar or set down at the piano and play something. I have long ceased getting angry about money issues and music. I play because I want too and I may be for hire but I am not for sale. I have played a lot of free gigs because I would rather do that than be angry about being offered $100 bucks to drive fifty miles one way to some bar to play.
I also do other things so music does not define me. When I get fed up with the crap that goes on in the music business I go fishing or go fly my airplane or go drive my buddy's tractor at his farm.
I also sometimes find when I get depressed with music and feel nobody is paying any attention to stuff I do it is because I have refused to get off my butt and get better at something I know I need to learn.
It is my business to create music and it is none of my business what other people think about what I create. I hope they like it, and it always feels good to get positive feedback.
Lighten up and take a break, and when you feel better, then you can make a decision about
"give up on music all together"
Cheers, Billy