2. "Also, should the number in my I/O buffers be the same as the number of my ASIO level of my Focusrite interface? Meaning if I change one, should I change both settings?"
I would think the answer to this would be yes, the two should match. If it was me, I would change the settings on the Focusrite first, and then see if Sonar settings change when you click "apply". I don't know if they will match exactly, but if the settings in sonar change, I would leave them. sonar could be reading your sound card settings and making some adjustments...
If you can change Sonar's buffer or samples settings independent of your soundcard (I cannot do this with mine), and sonar's settings don't change when you apply the Soundcard's changed settings...then my first inclination would be to match them both (manually). (edited)
BTW that video posted two posts up was very enlightening.