Another way to trouble shoot that comes to mind is
First go to Preferences/ MIDI devices and unselect all outputs for midi.
This will then automatically insert the TTS_1 when you OPEN any downloaded midi file.
So it will play without issue as a multi track, multi channel song. Never had this not work for me.
Now track by track you replace the TTS_1 with other instruments.
I use the SI bass a lot and always you have to transpose up 12 or it will be below it's range for many notes.
And it runs on what ever the channel originally was as far as my experience goes, I've never had to change the channel.
What scook has mentioned is then the only other reason it goes silent.
That's easy to test by just using the GUI to test it for playback, pluck a note.