As TheSteven pointed out, make sure you look over the default exclusions.
I always remove these and back up everything.
It's been a while since I had Acronis 2013 so I don't remember what it could or could not do.
The NTFS file system, the GPT and MBR partitioning systems have been around for some time.
Any back up system that understands them should be able to backup Windows 10.
If you use some of the newer Windows 10 features that use ReFS (like Storage Spaces), I don't think very many products will back that up. That's a completely different file system.
When a program says it is designed for Windows X, that usually just refers to the GUI and Windows APIs.
Most of the file system stuff has been unchanged since Windows XP. I think GPT booting is newer, but that is still fairly old.
I'm no file system expert, this is just my take on the subject.
I have updated Acronis products as soon as they came out, but this year I think I'll stick with Acronis 2016.
I don't see anything I want in the features.
The product is reaching critical bloat stature and has a lot of unnecessary parts and services.
All I want is full drive image backup and restore on demand. No schedules, no cloud, no continuous backup, no sync, nada.