Been a while since I used Acronis, but really any disk imaging program is capable of this (with exception of detection of a failing drive), and definitely better than nothing when you need it.
I use Marcrium Reflect now, but not pushing that brand, just stating this for clarity so that my comments are in context. Acronis users may want to jump in with their methods.
I set up a separate backup job in Macrium for each internal drive on my PC, and schedule it to run automatically. The target drive is an external USB3 drive that stays connected to my PC full time. Which drives get backed up when is up to you, but I do my system SSD 'C:' drive daily. I retain three days worth of full daily images here (3 most recent image files).
I also do a weekly backup of my system drive to a 2nd external USB3 drive that is always removed from my system and stored in a safe location. This is a redundant backup that covers loss, damage, theft, or corruption of the drive with the daily images. I always keep two weeks worth (2 most recent image files) of full weekly images here. So at most I might lose a week.
I also have image jobs scheduled for my data drives (content, samples, loops, downloads, installers, etc.) that I run weekly onto the 2nd external drive. This data doesn't change frequently enough to require daily backups, and most of it could be restored from original installers.
You can create folders with relevant names on your external backup drives for each backup job, so you will know right where to look for the image files you will need to restore from if that is ever necessary. You can set the max number of image files to retain for each image job, so that you can manage the space requirements on each backup disk. There will typically be some space compression on the image file, so they can be somewhat smaller in size than the source disk, but you will still need plenty of space to image everything. Multi-TB USB3 drives are getting cheaper by the day, so shouldn't be a showstopper!
The bottom line is that the loss of any internal drive could be remedied with a replacement drive and a few minutes of image restore time, rather than the downtime involved with re-installing everything on the drive. Priceless!!!