1) Download and install
AutoHotkey. The 64bit default location is "C:\Program Files\AutoHotKey"
2) Run AutoHotkey.exe (It may launch automatically I do not remember if it does)
3) There will be

in your notification area
4) Right-click the

to get this popup menu

5) Select "Edit This Script"
6) The default autohotkey script is loaded into notepad.
7) Add the two lines
#r:: send {Space}^zr#t:: send {Space}^{Home}rto bind the Windows+R and Windows+T key combinations to those two functions
8) Save the file
9) Right-click the

again and select "Reload This Script" to make the two scripts active.
Anytime AutoHotkey is running and those key combinations are hit, the keystrokes will be sent.
AutoHotkey can be run automatically at boot up by adding a shortcut to "C:\Program Files\AutoHotKey\AutoHotkey.exe" into "
yourUserDirectory\AppData\Roaming\Microsoft\Windows\Start Menu\Programs\Startup"