I think the issue on the Presonus forum was subtly different - it's the same signal, but theirs is within the system and coming out of the speakers. With my case, it's radiating from the PC and being collected by my guitar.
I don't think cables are an issue - the noise comes from the PC rather than the cable. I've tried with the cable from my old printer, but usually I use the cable that came with the interface with the ferrite core on the end - no difference either way.
Regarding the other questions - I'm usually about 2 or 3ft from the PC. I can get about 6 or 7ft from the PC at best, but the noise is still too loud, and that makes it a lot less practical to do short takes anyway. Different orientations help but not enough.
My guitar pickups are theoretically already well-shielded (EMG 81s and 60s) but obviously they are also just big magnets at the end of the day, and there's only so much the shielding can do.