i've built (or, had commissioned) 4 custom guitars....
3 strat style, one unique hybrid.
and all of them are completely different from each other, even when the body dimensions were the same......
there are so many variables that make a guitar sound the way it does, i don't think you can boil it down to body shape.
i've played 5 2008 VOS standard les pauls, back to back, and they ALL sounded and felt different.
same models, different color finishesj (and one had a different set of pickups), but acoustically, they were all different.
same woods, etc.....
some guys want a gretsch....
and you will not get that tone out of a strat....
etc etc, ad naseum.
i think ultimately, the 'why's?' don't matter as much as the hunt and discovery of one that really grabs your interest.
figure out WHY you like a certain thing, and then hone in on the ULTIMATE version of it.
you can buy a used Squire for, what, $90?
why does a guy spend $2500 on a vintage reissue strat?
$6500 for a 2014 reissue VOS 59 les paul?
Epiphone tribute plus paul for $699?