Audio technology Magazine (Australia) ran a great article in Feb 2014 issue that talk about a similar concept except rather than just look at the software only they looked at techniques and technolgy a bit more. They called these things the Game Changers. This to me seems a little more relevent. Here are some of the things they suggested were real game changers.
24 bit digital recording (done right)
DAW Development
(in two directions though. Tape Machine mixer model and electronic instrument sequencer model) PT lead the way for a long time in the Tape machine/mixer model concepts) Ableton Live and Fruity Loops brought in a different crowd
DSP powered plugins brought ITB mixing to life
Mackie HUI interface
Automation without any zipping
Giga sampler with its non ram limited approach ie disc streaming
Sample replacement
Track comping
Time and pitch manipulation
DAW's that cost under $100
DAW wise it is silly to compare a whole lot of DAW's. PT really started the Tape Machine/Mixing model and Cubase/Logic probably started the instrument/sequencer model.
(I was around then! Remember Steinberg VST technology etc) All other DAW's are simply developments of those basic two approaches so it pointless to compare them. I think what has happed now is that DAW's are blending the two approaches rather well now eg Sonar and many others etc... Of course these are more recent innovations, there were plenty of game changers before them too.