I was watching an Omnisphere tutorial and Eric Persing himself made a guest appearance, stating the some exciting things were coming in 2014. I presume will include a successor to or a major upgrade to Omnisphere.
Also, Camel Audio has long been talking about an Alchemy 2.0, which will probably enjoy a 2014 release date. And then there's Zebra 3.0 from u-he, also expected in 2014.
Let's see ... Kontakt didn't get any major upgrades in the last Komplete upgrade, did it? So, probably that's going to happen as well.
Start saving your pennies. I don't know about you, but I certainly won't be able to say no to any of these. And I'm probably leaving something else major out of the list.