Glyn Barnes
My biggest problem I experience is making out a conversation when there is a lot of background noise. I don't notice any issues when listening to music, but probably compensate by turning up the treble a bit more than I used to.

I've always played my stuff as if it had cleaner and clearer highs and lows. I like the contrast, and thus I usually turn the highs that way a bit so they are sharper, but I have done that for 40 years, and I can not say that I am not hearing them.
 
IF ... there is a major difference, it is that I am listening more things through the computer instead of the speakers and stereo, and guess where that difference is HIGHLY VISIBLE and NOTED! We might be losing something, but in essence what we have lost the most is the hi-fi experience for enjoying the music.