I am a bit of a regular user now so I can give you my ideas. I use Studio One and create all the music there and get it to the point of not doing anything more to the music but just about to mix.
I create stems of the buses and some tracks. Leave any broad based EQ alone and do that in Mixbus. Also you can afford to not use dynamics either on tracks and buses (in your DAW) because you can do that inside Mixbus too. I am not a fan of the limiter or compression much on the masterbuss. Leave that for a mastering session later.
You may want to print any reverb returns as well as special surgical or special tone shaping EQ in your tracks or stems before hand. Many of your VST's will open up inside Mixbus. You could still add the reverbs there too if you wanted too but I am not at this stage. They make a classy reverb too but it means buying it.
Mixbus will just bring the tracks and stems mainly together and it sounds fabulous doing it. Tape Sat can be used although the trick is to not get that smashing or distorting. Use it mildy. Tape SAT works with or without compression it does not depend on that.
It is very cool and your tracks will sound better for it. The EQ's and dynaimcs are very smooth and nice sounding inside Mixbus. You can then export your final mix from there and master in a later session. I also have the mastering EQ and Multiband comp and they both work very very well and also sound great too.
Mixbus can be used for just mastering a stereo stem too of a whole mix. It still sounds great even doing that. It is easier and faster to mix inside Mixbus than anything. You will see why once you get inside it and start using it. I like it too because it is all set up for K system metering and the ref level has been set at a fixed K-14 which is what I work at a lot of the time so that is great for me.
It is very much like taking your session to a hardware based studio with a Harrison console and that cannot be bad in any terms. It gets you out of your DAW for the mix which is also healthy and lets you focus on just the mix and nothing else. It is way fast and fun to use.