It sort of depends on how much you are talking about. Have you got any idea at all what this job is worth? If I was transferring a tape to CD or something like that and the cost was going to be $250 or even $500 I doubt I would ask for a down payment.
Once the size of the job gets to say $1000 then I just say to the client a down payment is needed to get started.
(I often ask for a third up front, a third about half way through and the final third on completion. If a job spans several months then we work out a payment plan. It is very important to have money coming in on a regular basis over a longer job) How much do you think the job is worth to you? What is their budget? Are they the same? Probably not.
Money is very important and you need to get that sorted out first!! You might think the job is worth $2000 and they might think the job will cost $200. Don't get all the way to the end to find that out please. Find out before you start. Then you might save a whole bunch of time.
If you cannot handle the money side of the business then you are not going to make it producing music professionally and getting paid to do so. Professional music production is very much a business thing too. Musicians are notorious for being terrible in this area. Learn about it!
Clients actually like it when you are confident and direct about money. It instills confidence in them in you.