I have an Epiphone dot (335) and the full TH2. I have had a look on youtube, and some seem to recommend neck pick up with tone fully open, then pull the treble and bass down, and left the mid up 1 or 2 on the amp. I'm guessing part of my problem is at my finger tips, andd this will come, but what setting would be a good start. What amp in TH2, and how would you suggest setting it.
 
I can't get flatwounds here, and my strings are new. When I get out of this hotel, and into my apartment, I'm going to order some monitors from Thomann, so I think I'd get some flatwounds in the same order.

I suppose the first question is what or who you mean by a "classic jazz tone"? Joe Pass and Django Reinhardt both recorded with electric guitars (well, guitars with pickups connected to an amplifier) and both were virtuosos with very "classic" jazz tones but sound nothing alike.

Speaking in very broad terms - you have a good starting point w/ a semi hollow. When I think classic jazz, I think of a very smooth guitar sound, with very little treble - so you'll want to roll it off either on the guitar, either on the amp. Typically, I'd use the neck pick-up, sometimes both pick-ups.
 
I don't own TH2, but I'm guessing that you'll typically want to opt for older, classic models of Fender amp - Gibson if that's an option.  I mean, you could probably use just about any model, a Boogie or Engl. But an old Fender will typically narrow down your palette to something that's already in the ballpark.
 
I have a very approximative notion of jazz guitar sounds, fairly old-school - so I'm thinking generic, along the lines of Charlie Christian, Wes Montgomery, etc... But modern players I've seen also seem to favour that trebel-less type of sound.

Thanks for the replies guys, sorry I got kicked out of the country for a bit, and went to Kuala Lumpur untill they'd let me back in.
 
Yeah that's more the idea I'm after Rain, a generic sound, rather than emulate a specific player. But it's more the older sounds than the modern fusion style players. One player I particularly like is Kenny Burrell, but even then It's not his sound I'm trying to recreate. In one youtube video I watched, the guy instructing described it as the 'bloopiness'.
 
As the TH2 amps don't reverence fender/gibson, anyone here who nows the amps available, can they make some suggestions what to try, and the settings they would use. Some include thing like 'edge' which I believe is just treble.
 
I'm more looking for suggestions of things to try. Once I get in the ball park I can start taking it in a more personal direction.  

do TH2 have a bass amp or preamp?
Also might do the trick (if bass amp, have the tone knob on full)

I just checked their web page, and these would be my most obvious pick:
 
Bassface '59 (US) - which is modelled on a Fender '59 Bassman
Darkface '65 (US) - Fender Twin
Top30 (UK) - Vox AC30
Rock '64 (UK) - Marshall JTM-45
 
I'm not sure in which order. But that's where I'd start. 
 
Randall Tweed, which seem to be a model of a model of an old Fender, such as a Fender Champ caught my eye. A Champ would be one of the best options, imho. 

Thanks Rain, sorry I guess I should have tried the same. Being utterly clueless on amps, I thought the TH2 names were the actuals names of amps from old.

kristoffer
do TH2 have a bass amp or preamp?
Also might do the trick (if bass amp, have the tone knob on full)

I don't think so, I think the MarkBass covers that ground. Kicking myself I didn't buy that in the looney sales from 2 months ago, as somewhere between here and Germany I have a Squire JazzBass shipping its way to me.
 

When I think of "classic jazz tone" I see an ES-335 plugged into a Fender twin tube amp with rolled off highs, a clan low end and a slight mid boost, and nothing cranked excessively to get into distortion, and a hint of reverb.

Cool, I'll try the Darkface and Randall Tweed first when I get a moment