This is a somewhat aging thread, but I decided to check it out.
I have two monitors, both set to 1600x900. At this resolution, fonts are clear, and all of my GUI's fit on the screen.
I don't have Z3ta+2, but Z3ta+ is actually smaller than most of the other synth GUI's(may not be relevant).
As to being "detachable" you should be able to dock or float it just as any other synth GUI.