The latency/IO buffers are a system specific thing that has a "sweet spot" that is system dependent. I just ran back through the thread quick but did not see what driver mode, and audio interface you are using. These also play into the overall picture. Realize that "maxed out" buffers can be just as bad as too small.
As far as finding the sweet spot for your system, it is good to take a fairly intensive project (the
X3 demo project is a good choice) and use that for tailoring these.
ASIO mode with drivers specific to your interface are highly preferred. WDM mode is a best second, and anything other than these two tend to cause issues for most people (in general).
Start with the ASIO buffer at 128 (Preferences->Audio->Driver Settings->ASIO Panel...), and I/O buffers at 512 (Advanced Mode: Preferences->Audio->Synch and Caching)
- Set preferred audio buffer.
- Start playback.
- If it drops out or other issues adjust I/O buffers in steps of 256.
- Repeat steps 2 & 3. Try adjusting buffers both up and down until happy. 256 jumps should do.
- If after trying all sizes up to 1024 you still have issues go back to step 1 and increase audio buffer to the next available setting (these are often "locked" to something like 128, 192, 256, 384, 512, 768, 1024, 2048).
- Repeat as necessary until you find the "magic" combination for your setup.
The default settings of 128/512 usually fit most scenarios fairly decently.
As mentioned above, the driver mode you are using, and audio interface can also make a massive impact on "system," depending what they are.