Well I gave it a good bash for a couple of days, didn't do much more comparing against AmpliTube 3 after the initial comparison with the Mesa/Boogie, which did sound better to me in AmpliTube 4. I didn't mind the Red Pig, and the Brit Silver, but apart from that I didn't think much of the other amps. I think AmpliTube 4 is certainly better than, a step up from AmpliTube 3, I was never that keen on AmpliTube 3 to start with, although I do like the Orange Collection and a few other amps like the ENGL, Soldano, and a few more. What I did find is that after a couple of days just playing with AmpliTube 4, when I switched to BIAS FX Pro, the difference was immediate, it's like a slap in the face, BIAS just sounds better straight up, better sound quality, just better is all I can say.
 
I see a lot of people who like Amp3/4's Fender amps, I have never liked them, in fact always thought they sounded like sh!te, so I fired up a '67 Blackface and a '59 Tweed Deluxe in BIAS FX Pro, played them for a while and compared them to the Fender Collection, again, to my ears there is no comparison, the difference to me is immediate and unmistakable, it just sounds better, a better quality of sound, I don't know, that's the best I can describe it, whether or not 1 or the other sounds more authentic or not, I don't know, and whether or not they are modeled after a certain amp or not I don't know, but it's easy to tell they were both shooting for a similar target, and to be honest it doesn't matter to me whether the BIAS FX Pro version was modeled after a falling tree branch, the fact is it just sounds better, full stop. And it's not just sound, it's a feel as well if that makes sense.
 
I said earlier that I wouldn't have paid full price of $149 for AmpliTube 4, and that I wasn't sure if the pre order price $99 was worth it, well, if I had my time over again, I would just skip it all together, it's not really worth it to me, I have stuff which is so much better, stuff I can get far better tones out of. And to whoever it was above who suggested a price of $49 or whatever for AmpliTube 4, I'd say yeah, that would be about right.
 
So I have now removed AmpliTube 3 and 4 and all associated stuff, I won't be updating them any longer or maintaining them or spending any more time money on them, I had hoped, but unfortunately AmpliTube just isn't up there with leaders of the pack in my view. I have had a bit of a clean out, S-Gear 2, Revalver 3dot5 and 4, Guitar Rig 5, Recabinet 4, Vandal, AmpLion Pro (rolls eye's) have all been removerd, I'm just keeping BIAS Amp Pro, BIAS FX Pro, TH2, the Kuassa Amps, TSE, GTR 3.5 and a few excellent freebies like Ignite Amps and LePou. I'll continue to get whatever comes along and looks to be good, but if they don't stack up just uninstall them and put them in the pile. Not really into demos, the only way is with the full product and no restrictions.
 
Hopefully TH3 might be just around the corner, there are a few whispers, but . . . here's hoping. Oh and check out BIAS Pedal for any distortion needs, it really is very AWESOME in that area, I have been using it for a while via the explorer program, it was released a couple of days ago, it kicks major arse, and much fun to boot.

I think sometimes we tend to forget that EVERYONE's needs are different! It has never been a matter of this product being better than that product. It will always be about finding the tool that satisfies YOUR needs and then trying to get as much knowledge as possible how to use that tool.
Something else that is critical that hardly anyone thinks about is that no two people have the same hearing perception! Everyones ears are PHYSICALLY shaped different just like fingerprints, or so I was told. For this reason someones perception of what sounds great may not sound the same to the person standing next to you. I lean more towards more melodic playing than shredding. My needs are met better by a product that doesn't always fall in to full blown sheets of distortion. Though, to satisfy my clients I may need that sound from time to time. I think sometimes we forget that it's about versatility for a lot of us guitarist. 
We use what we must in studio work to get the finished results. Whatever works for one may not work for the other. Find what works for you and stick with it but we shouldn't just dismiss other tools that may very well be better for some situations than others. If one tool works for everything you do, GREAT! I find myself using many diverse combinations of amp sims and like the differences between them.
I'll shut up now. I can see the shark fins circling around me. Just an observation, fellas!